I believe most higher octane fuels have reduced/no ethanol added. However, my experience with ethanol fuel here in NJ is that the main changes needed are:
(1) Replace all rubber seals with viton in the fuel lines, fuel pump, carbs and reserve tap. This includes the rubber fuel line hose.
(2) Look out for fuel boiling on hot days. Ethanol lowers the boiling point causing floats to sink in the carb and pour fuel out. It took me a fair while to diagnose the issue and cured it with additional heat shielding.
(3) As mentioned above, E fuel has less energy per gallon compared to regular. I found going richer with the carb needles helped solve that issue.
Otherwise, I think that was about it. If you plan on leaving the car standing for a few months a fuel stabiliser would be a good idea. Ethanol absorbs water that can start rust in the tank. It also degrades and will cause poor running and varnishing. Stabilisers will help mitigate both those problems.